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BLNK Rabbit anti-Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA119377
DescriptionSLP65 / BLNK (SH2 domain-containing leukocyte-specific phosphoprotein of 65 kDa; B cell linker protein), also known as BASH, is an adaptor protein that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). Phosphorylated by Syk tyrosine kinase, SLP65 serves as a scaffold for Btk tyrosine kinase, Vav1 guanine nucleotide exchange factor, phospholipase C gamma2, as well as Grb2 and Nck adaptor proteins; thus represents a central linker protein that bridges the BCR-associated kinases with a multitude of signaling pathways.
|PBS with 15mM sodium azide; pH 7.4|
|BLNK; BASH; BLNK-s; Ly57; MGC111051; SLP-65; SLP65; B cell linker protein; SLP-65|
|4° C, do not freeze|
|Fusion protein corresponding to residues 171-356 of human BLNK.|
|Ammonium sulfate precipitation|
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