BMI-1 Mouse anti-Human, Clone: 384515, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524123
Reconstitute at 0.5 mg/mL in sterile PBS.Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A ft.Lys-119 ft., rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
|PBS with 5% trehalose and No Preservative|
|BMI1, PCGF4, RNF51, Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51|
|-20° C, Avoid Freeze/Thaw Cycles|
|ChIP assay, Flow Cytometry, Western Blot|
|E. coli-derived recombit human BMI-1 Asp96-Gly326|
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