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BMP-6 Mouse anti-Human, Clone: 74219, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523844

Catalog No. PIMA523844



Description

Description

In Western blots, no cross-reactivity with recombit human (rh) BMP-2, rhBMP-4, rhBMP-5, or rhBMP-7 is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
Specifications

Specifications

BMP-6
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P22004
VGR, VGR1, BMP-6, VG-1-R, VG-1-related protein, VGR-1, Vg1-related sequence, vegetal related growth factor (TGFB-related), vegetal-related (TGFB related) cytokine
Mouse
IgG2B
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
654
ELISA, Neutralization, Western Blot
74219
Unconjugated
BMP6
Lyophilized
BMP6
CHO-derived recombit human BMP-6 Arg296-His428
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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