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CDw293 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527712

Catalog No. PIPA527712


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Description

Description

PA5-27712 targets BMPR1B in WB applications and shows reactivity with Human samples. The PA5-27712 immunogen is recombit fragment corresponding to a region within amino acids 238 and 502 of Human BMPR1B. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.
Specifications

Specifications

CDw293
Polyclonal
Unconjugated
BMPR1B
Liquid
BMPR1B
Recombit fragment corresponding to a region within amino acids 238 and 502 of Human BMPR1B
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
0.1 mg/mL
PBS with 20% glycerol and 0.025% Proclin 300; pH 7
O00238
ALK-6, ALK6, CDw293, BMP type-1B receptor, BMPR-1B, activin receptor-like kinase 6, bone morphogenetic protein receptor type-1B, serine/threonine receptor kinase
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
658
Documents
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