BNIP3 Rabbit anti-Human, DyLight® 550, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA522863
In Western blot a band is seen in hypoxic samples at ~30 and 60 kDa, representing the BNIP3 protein. There are some non-specific bands present as well. It is recommended that normoxic samples are run next to the hypoxic samples as a negative control.This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. This gene contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2.
|A synthetic peptide against an N-terminal region (within residues 1-50) of the human BNIP3 protein.|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|sodium borate with no preservative|
|NIP3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3|
|4° C, store in dark|
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