anti-BNIP3L Polyclonal, Thermo Scientific™

BNIP3L Polyclonal antibody PA1-12514 from Thermo Scientific™ specifically detects BNIP3L in Human samples, and it is validated for Western Blot

Manufacturer: Thermo Scientific PA112514

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Catalog No. 01-674-174

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    Specifications

    Antigen BNIP3L
    Applications Western Blotting
    Conjugate Unlabeled
    Cross Reactivity Human
    Format Purified
    Formulation 100μg purified Antibody in PBS, with 0.02% sodium azide;
    Gene Accession No. O60238
    Gene Alias BNIP3a, NIX
    Gene Symbols BNIP3L
    Host Species Rabbit
    Immunogen Synthetic peptide corresponding to residues 77-92 of human Bnip3L.
    Isotype IgG
    Quantity 100μg
    Species Reactivity Human
    Storage Requirements Avoid Freeze/Thaw Cycles
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Gene ID (Entrez) 665

    BNIP3L Polyclonal antibody PA1-12514 from Thermo Scientific™ specifically detects BNIP3L in Human samples, and it is validated for Western Blot

    Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3a, and Nix (for Nip3-like protein X Bnip3L/Bnip3a/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria.
    Host Species: Rabbit
    Cross Reactivity: Human
    Isotype: IgG
    Immunogen: Synthetic peptide corresponding to residues 77-92 of human Bnip3L.
    Formulation: 100µg Purified Antibody in PBS, with 0.02% sodium azide
    Synonyms: BNIP3a, NIX
    Uniprot Accession: O60238
    Entrez GeneID: 665
    Gene Symbol: BNIP3L
    A suggested positive control for this product is K562 cell lysate.

  • Description & Specifications

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