BNIP3L Polyclonal Antibody, Invitrogen™

BNIP3L Antibody, PA1-12514, from Invitrogen™. Species Reactivity: Human; Applications: Western Blot.

Manufacturer: Invitrogen PA112514

Catalog No. 01-674-174

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    Formulation 100μg purified antibody in PBS and 0.02% sodium azide
    Gene ID (Entrez) 665
    Gene Accession No. O60238
    Gene Alias BNIP3a, NIX
    Gene Symbols BNIP3L
    Applications Western Blotting
    Species Reactivity Human
    Storage Requirements Avoid Freeze/Thaw Cycles
    Format Purified
    Host Species Rabbit
    Immunogen Synthetic peptide corresponding to residues 77-92 of human Bnip3L.
    Cross Reactivity Human
    Antigen BNIP3L
    Isotype IgG
    Quantity 100μg
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Conjugate Unlabeled

    BNIP3L Antibody, PA1-12514, from Invitrogen. Species Reactivity: Human; Applications: Western Blot.

    Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3a, and Nix (for Nip3-like protein X Bnip3L/Bnip3a/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria.
    Host Species: Rabbit
    Cross Reactivity: Human
    Isotype: IgG
    Immunogen: Synthetic peptide corresponding to residues 77-92 of human Bnip3L.
    Formulation: 100µg purified antibody in PBS and 0.02% sodium azide
    Synonyms: BNIP3a, NIX
    Uniprot Accession: O60238
    Entrez GeneID: 665
    Gene Symbol: BNIP3L
    A suggested positive control for this product is K562 cell lysate.

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