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BPDE Mouse anti-Chemical, Clone: 8E11, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA140270

Catalog No. 01-676-389


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Description

Description

This antibody recognizes free BPDE and DNA adducts.

A number of chemicals, including polycyclic aromatic hydrocarbons (PAHs), have been shown to bind to DNA. This DNA damage can occur both early and late in the maligt process, thereby acting as an initiator and assisting in the progression of tumors. PAHs are released into the environment following incomplete combustion of organic materials. The most common sources of PAHs are from smoking and from consuming broiled or grilled foods. Human exposure to PAHs comes from various occupational, environmental, dietary and medicinal sources. Benzo[a]pyrene is a representative PAH. Antibodies to benzo[a]pyrenediol-epoxide modified DNA (BPDE-DNA) can be used to identify polycyclic aromatic hydrocarbon (PAH)-DNA adducts. Exposure to this group of compounds is believed to be carcinogenic.
Specifications

Specifications

BPDE
Monoclonal
0.1 mg/mL
PBS with 0.1% BSA and 0.02% sodium azide
Benzo[a]pyrenediol-epoxide; BPDE
BPDE.
Purified
RUO
Antibody
Monoclonal
ELISA
8E11
Unconjugated
Liquid
Mouse
IgG1
100 μg
4° C
Primary
Chemical
Documents
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