MilliporeSigma™ anti-Brachyury, Clone: 3E4.2, ™ (Upstate™)

Supplier:  MilliporeSigma™ 04135/DEL

Catalog No. 50-171-255

Description

The Brachyury protein is a T-box transcription factor that is one of the earliest indicators of mesoderm formation during embryonic development. As the brachyury protein family is essential for the formation of the posterior body in all vertebrates, Brachyury has been shown to be expressed during gastrula and neurula stages, as well as in the developing notochord. Consequently, when mutations occur within the brachyury gene, severe vertebral malformations have been found to occur, as a direct result. In addition, current findings also indicate that the dysregulation of brachyury may also be linked to the formation of chordomas, which are malignant tumors that develop along the spine.

Host Species:Mouse
Clone:3E4.2
Isotype:IgG1κ
Species Reactivity:Human
Epitope:C-terminus
Immunogen:Recombinant GST-TAL1
Molecular Weight:47kDa

Western Blotting

Specifications

• Antigen: Brachyury
• Concentration: 1mg/mL
• Host Species: Mouse
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Semi-purified

• Classification: Monoclonal
• Conjugate: Unconjugated
• Quantity: 100 μg
• Research Discipline: Stem Cell Biology
• Target Species: Human
• Isotype: IgG1 κ