BRAF35 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA14192
PA1-4192 detects BRAF35 in human samples. PA1-4192 has been successfully used in Western blot procedures. The PA1-4192 immunogen is a synthetic peptide corresponding to residues K(31) Q E R G E G P R A G E K G S H E E E P(50) of the human structural DNA-binding protein BRAF35. This sequence is 80% conserved in mouse.Mutations of the human BRCA2 gene confer susceptibility to breast cancer. A structural DNA binding component has been identified and is designated as BRCA2-Associated Factor 35 (BRAF35). There is a close association of the BRAF35/BRCA2 complex with condensed chromatin coincident with histone H3 phosphorylation. Experimental evidence suggests a role for the BRCA2/BRAF35 complex in the modulation of cell cycle progression.
|Synthetic peptide corresponding to residues K(31) Q E R G E G P R A G E K G S H E E E P(50) of human BRAF35.|
|Antigen affinity chromatography|
|PBS with 0.02% sodium azide|
|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related, SMARCE1-related protein, HMG domain protein HMG|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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