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C/EBP beta Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527244

Catalog No. PIPA527244


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Description

Description

PA5-27244 targets C/EBP beta in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27244 immunogen is a synthetic peptide corresponding to a region within amino acids 1 and 95 of C/EBP beta. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
Specifications

Specifications

C/EBP beta
Polyclonal
Unconjugated
CEBPB
Liquid
CEBPB
Synthetic peptide corresponding to a region within amino acids 1 and 95 of C/EBP beta
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
ChIP assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
1 mg/mL
PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
P17676
C/EBP-beta, CRP2, IL6DBP, LAP, NF-IL6, TCF5, CCAAT/enhancer-binding protein beta, TCF-5, interleukin 6-dependent DNA-binding protein, liver-enriched transcriptional activator protein, nuclear factor NF-IL6, nuclear factor of interleukin 6, transcription factor 5
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
1051
Documents
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