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C2 Rabbit anti-Hamster, Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA524158

Catalog No. PIPA524158

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Component C2 is a serum glycoprotein that functions aspart of the classical pathway of the complement system. ActivatedC1 cleaves C2 into C2a and C2b. The serine proteinase C2a thencombines with complement factor 4b to create the C3 or C5convertase. Deficiency of C2 has been reported to associated withcertain autoimmune diseases and SNPs in this gene have beenassociated with altered susceptibility to age-related maculardegeneration. This gene localizes within the class III region ofthe MHC on the short arm of chromosome 6. Alternative splicingresults in multiple transcript variants encoding distinct isoforms.Additional transcript variants have been described in publicationsbut their full-length sequence has not been determined.
Specifications

Specifications

C2
Polyclonal
PBS with 0.09% sodium azide
P06681
CO2, C3/C5 convertase, complement C2, complement component C2
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
100759069, 717
Western Blot
Unconjugated
C2
Liquid
C2
KLH conjugated synthetic peptide between 147-176 amino acids from the N-terminal region of human C2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Hamster, Human
Documents
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