Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Complement C5a Rat anti-Mouse, Clone: 295108, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523910

Catalog No. PIMA523910


Add to cart

Description

Description

In Western blots, this antibody does not cross-react with Recombinant mouse Complement Component C3d, Recombinant human (rh) Complement Component C3a, or rhComplement Component C5a. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis.
Specifications

Specifications

Complement C5a
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P06684
CPAMD4, FLJ17816, FLJ17822, MGC142298
Rat
IgG2A
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
15139
ELISA, Neutralization, Western Blot
295108
Unconjugated
Hc
Lyophilized
Hc
E. coli-derived recombit mouse Complement Component C5a Asn679-Arg755
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit