Carbonic Anhydrase IX Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA513084
DescriptionCarbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
|Carbonic Anhydrase IX|
|PBS with 0.09% sodium azide|
|Carbonic anhydrase 9 [Precursor]; Carbonic anhydrase IX; Carbonate dehydratase IX; CA-IX; CAIX; Membrane antigen MN; P54/58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1; CA9; G250; MN;|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic peptide between 63-90 amino acids from the N-terminal region of human CA9|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
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