CaBP8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521002
A suggested positive control is NIH-3T3 cell lysate. PA5-21002 can be used with blocking peptide PEP-1116.Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70% homology with CaBP7 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.
|A 16 amino acid peptide near the amino terminus of human CaBP8.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|PBS with 0.02% sodium azide|
|Q9BXU9, Q9JJG7, Q06BI3|
|CABP8; calcium-binding protein 8; calcium-binding protein CABP8; calneuron I; calneuron-1|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|140904, 363909, 83698|
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