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CACTIN Rabbit anti-Bovine, Canine, Human, Non-human primate, Porcine, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523500

Catalog No. PIPA523500


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Description

Description

Cactin is a novel negative regulator of TLR signaling and reveals its capacity to target MHC Class III genes at the molecular and functional level. It is localized to the nucleus, which is critical for manifesting its inhibitory effects on TLR signaling. Experimental evidences show overexpression of Cactin suppresses TLR-induced activation of NF-kB and interferon-regulatory factor transcription factors and induction of TLR-responsive genes. It is also reported Cactin interacts with IkB-like protein and targets other proteins that are encoded by genes in the MHC Class III region of chromosome 6.
Specifications

Specifications

Cactin
Polyclonal
PBS with 0.05% BSA and 0.05% sodium azide
Q8WUQ7
NY-REN-24, cactin, fSAPc, NY REN 24 antigen, NY-REN-24 antigen, cactin homolog, functional spliceosome-associated protein c, renal carcinoma antigen NY-REN-24, uncharacterized protein C19orf29
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100521180, 485055, 58509
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
CACTIN
Liquid
CACTIN
Synthetic peptide (478 PLFPILKQEPQSPSRSL 494) of Cactin protein.
Protein A
RUO
Antibody
Polyclonal
Bovine, Canine, Human, Non-human primate, Porcine
Documents
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