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H-cadherin Rat anti-Human, Mouse, Clone: 392411, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA524128

Catalog No. PIMA524128


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Description

Description

In direct ELISAs and Western blots, no cross-reactivity with recombit human (rh) E-Cadherin, rhN-Cadherin, rhP-Cadherin, rhVE-Cadherin, rhCadherin-8, -11, -12 or -17 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintece of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. T-cadherin (for truncated-cadherin, also designated heartcadherin or cadherin-13) expression levels have been shown to be reduced in human breast cancers and carcinoma cells lines. Evidence suggests that.
Specifications

Specifications

H-cadherin
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P55290, Q9WTR5
CAD13, Cadherin-13, CDH13, CDHH, H-cadherin, Heart Cadherin, P105, T cad, T Cadherin, T-cad, T-cadherin, Truncated Cadherin
Rat
IgG2A
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
1012, 12554
Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
392411
Unconjugated
CDH13
Lyophilized
CDH13
Mouse myeloma cell line NS0-derived recombit human Cadherin-13 Glu23-Ala692
Protein A/G
RUO
Antibody
Monoclonal
Human, Mouse
Documents
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