H-cadherin Rat anti-Human, Mouse, Clone: 392411, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA524128
In direct ELISAs and Western blots, no cross-reactivity with recombit human (rh) E-Cadherin, rhN-Cadherin, rhP-Cadherin, rhVE-Cadherin, rhCadherin-8, -11, -12 or -17 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintece of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. T-cadherin (for truncated-cadherin, also designated heartcadherin or cadherin-13) expression levels have been shown to be reduced in human breast cancers and carcinoma cells lines. Evidence suggests that.
|PBS with 5% trehalose and No Preservative|
|CAD13, Cadherin-13, CDH13, CDHH, H-cadherin, Heart Cadherin, P105, T cad, T Cadherin, T-cad, T-cadherin, Truncated Cadherin|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry (Frozen), Western Blot|
|Mouse myeloma cell line NS0-derived recombit human Cadherin-13 Glu23-Ala692|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok