K-cadherin Mouse anti-Human, Clone: 427909, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524159
In direct ELISAs and Western blots, no cross-reactivity with Recombinant human (rh) Cadherin-8, -11, -12, -13, -17, rhECAD, rhMCAD, rhNCAD, rhRCAD, rhPCAD, or rhVECAD is observed. Reconstitute at 0.5 mg/mL in sterile PBS.This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintece of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.
|PBS with 5% trehalose and No Preservative|
|CAD6, KCAD, cadherin-6|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot|
|Mouse myeloma cell line NS0-derived recombit human Cadherin-6/KCAD Ser54-Ala615|
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