CAF1 p60 Mouse anti-Human, Clone: 1SS-48, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA191703

Catalog No. PIMA191703

Description

MA1-91703 detects CAF1A from human samples. MA1-91703 has been successfully used in immunofluorescence, immunoprecipitation, Western blot applications. The MA1-91703 immunogen is: Mice were immunized with human CAF-1 p130 subunit protein and fusing the splenocytes with P3-X63-Ag8-653 mouse myeloma cells. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.

Specifications

• Antigen: CAF1 p60
• Classification: Monoclonal
• Concentration: 0.75 mg/mL
• Gene: CHAF1B
• Gene Alias: CAF-1, CAF-IP60, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 8208
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
• Clone: 1SS-48
• Conjugate: Unconjugated
• Gene Accession No.: Q13112
• Gene Symbols: CHAF1B
• Immunogen: Mice were immunized with human CAF-1 p130 subunit protein and fusing the splenocytes with P3-X63-Ag8-653 mouse myeloma cells.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1