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Calcitonin Receptor Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA130120

Catalog No. PIPA130120


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Description

Description

PA1-30120 detects Calcitonin receptor from human, mouse, rat samples. PA1-30120 has been successfully used in immunohistochemistry (paraffin tissue) applications. The PA1-30120 immunogen is: Synthetic peptide derived from sequence of rat calcitonin receptor.

The Calcitonin Receptor inhibits bone resorption. This receptor is expressed during development and is involved in morphogenesis. Three alternatively spliced Calcitonin Receptor isoforms have been identified. In addition to binding calcitonin, the Calcitonin Receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes. The Calcitonin Receptor has been reported in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid. ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.
Specifications

Specifications

Calcitonin Receptor
Polyclonal
Unconjugated
CALCR
Liquid
CALCR
Synthetic peptide derived from sequence of rat calcitonin receptor.
Protein A
RUO
Antibody
Polyclonal
Human, Mouse, Rat
ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
1 mg/mL
PBS with 0.09% sodium azide; pH 7.4
P30988, Q60755, P32214
CRT, CTR, CTR1
Rabbit
IgG
10 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
116506, 12311, 799
Documents
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