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Calcium Sensing Receptor Rabbit anti-Human, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA137213

Catalog No. 01-673-146


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Description

Description

This antibody is predicted to react with bovine and mouse based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is placenta tissue.

The calcium sensing receptor (CaSR) has been shown to play a major role in regulating parathyroid hormone secretion and subsequently influencing the calcium concentration of extracellular fluids. Several disorders of calcium homeostasis have been linked to mutations in the CaSR. These include familial hypocalciuric hypercalcemia (FHH), neonatal severe hyperparathyroidism (NSHPT), and autosomal domit hypocalemia (ADHypo).
Specifications

Specifications

Calcium Sensing Receptor
Polyclonal
PBS with 1% BSA and <0.1% sodium azide; pH 7.4
P41180, P48442
CaSR antibody, Parathyroid Cell calcium-sensing receptor antibody.
Rabbit
IgG
1 mL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
24247, 846
Immunohistochemistry (Paraffin)
Unconjugated
CASR
Liquid
CASR
Synthetic peptide from N-terminus of rat calcium sensing receptor
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Rat
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