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Caldesmon Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527719

Catalog No. PIPA527719


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Description

Description

PA5-27719 targets Caldesmon in WB applications and shows reactivity with Human samples. The PA5-27719 immunogen is recombit fragment corresponding to a region within amino acids 1 and 203 of Human Caldesmon. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Specifications

Specifications

Caldesmon
Polyclonal
Unconjugated
CALD1
Liquid
CALD1
Recombit fragment corresponding to a region within amino acids 1 and 203 of Human Caldesmon
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
0.86 mg/mL
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Q05682
CDM, H-CAD, HCAD, L-CAD, LCAD, NAG22, caldesmon
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
800
Documents
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