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Mu-Calpain Mouse anti-Bovine, Human, Mouse, Rat, Clone: 15C10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA112434

Catalog No. 01-674-304


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Description

Description

The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and µ-calpain (calpain I ) are composed of an 80 kD subunit and a 30 kD subunit. Wheras the 30 kD subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names. Whereas m-clapain requires millimolar (mM) levels of calcium, µ-calpain is active at micromolar (uM) concentrations of Ca++. In addition to the ubiquitously expressed m- an µ- calpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
Specifications

Specifications

Mu-Calpain
Monoclonal
1 mg/mL
PBS with 50% glycerol and 3mM sodium azide; pH 7.5
Q27970, P07384, O35350, P97571
CaNP
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
12333, 281661, 29153, 823
ELISA, Immunoprecipitation, Western Blot
15C10
Unconjugated
CAPN1
Liquid
CAPN1
Human Calpain protein purified from placenta.
Protein A/G
RUO
Antibody
Monoclonal
Bovine, Human, Mouse, Rat
Documents
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