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Calpain 3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527721

Catalog No. PIPA527721


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Description

Description

PA5-27721 targets Calpain 3 in WB applications and shows reactivity with Human samples. The PA5-27721 immunogen is recombit fragment corresponding to a region within amino acids 623 and 821 of Human Calpain 3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
Specifications

Specifications

Calpain 3
Polyclonal
Unconjugated
CAPN3
Liquid
CAPN3
Recombit fragment corresponding to a region within amino acids 623 and 821 of Human Calpain 3
Protein A
RUO
Antibody
Polyclonal
Human
Western Blot
2 mg/mL
PBS with 40% glycerol and 0.01% thimerosal; pH 7
P20807
CANP3, CANPL3, LGMD2, LGMD2A, nCL-1, p94, calcium-activated neutral proteinase 3, calpain L3, calpain p94, large [catalytic] subunit, calpain, large polypeptide L3, calpain-3, muscle-specific calcium-activated neutral protease 3 large subunit, new calpain 1
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
825
Documents
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