Calreticulin Chicken anti-Canine, Hamster, Human, Mouse, Rabbit, Rat, Polyclonal, Invitrogen
Chicken Polyclonal Antibody
Manufacturer: Invitrogen PA1903
PA1-903 detects calreticulin from human, rat, mouse, hamster, rabbit and canine tissues. PA1-903 has been successfully used in Western blot, immunoprecipitation, immunocytochemistry and immunofluorescence procedures. By Western blot, this antibody detects an ~60 kDa protein representing calreticulin and an ~120 kDa unidentified protein from rat brain extract. PA1-903 immunizing peptide corresponds to amino acid residues 399-414 from mouse calreticulin. PA1-903 immunizing peptide (Cat. No. PEP-017) is available for use in neutralization and control experiments.Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.
|Synthetic Peptide: D(399) E K E E D E E E S P G Q A K D(414).|
|Antigen affinity chromatography|
|Canine, Hamster, Human, Mouse, Rabbit, Rat|
|Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|antibody with 1mg/mL BSA and 0.05% sodium azide|
|P28490, P27797, P14211, P15253, P18418|
|Calregulin, CRP55, CaBP3, Calsequestrin-Like Protein, Ro/SS-A Antigen|
|-20° C, Avoid Freeze/Thaw Cycles|
|100009050, 100689096, 12317, 476694, 64202, 811|
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