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Calreticulin Chicken anti-Canine, Hamster, Human, Mouse, Rabbit, Rat, Polyclonal, Invitrogen™

Chicken Polyclonal Antibody

Manufacturer:  Invitrogen PA1903

Catalog No. PA1903


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Description

Description

PA1-903 detects calreticulin from human, rat, mouse, hamster, rabbit and canine tissues. PA1-903 has been successfully used in Western blot, immunoprecipitation, immunocytochemistry and immunofluorescence procedures. By Western blot, this antibody detects an ~60 kDa protein representing calreticulin and an ~120 kDa unidentified protein from rat brain extract. PA1-903 immunizing peptide corresponds to amino acid residues 399-414 from mouse calreticulin. PA1-903 immunizing peptide (Cat. No. PEP-017) is available for use in neutralization and control experiments.

Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.
Specifications

Specifications

Calreticulin
Polyclonal
Unconjugated
CALR
Liquid
CALR
Synthetic Peptide: D(399) E K E E D E E E S P G Q A K D(414).
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Canine, Hamster, Human, Mouse, Rabbit, Rat
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
1 mg/mL
antibody with 1mg/mL BSA and 0.05% sodium azide
P28490, P27797, P14211, P15253, P18418
Calregulin, CRP55, CaBP3, Calsequestrin-Like Protein, Ro/SS-A Antigen
Chicken
IgY
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
100009050, 100689096, 12317, 476694, 64202, 811
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