Calreticulin Rabbit anti-Canine, Human, Mouse, Non-human primate, Rabbit, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA3900
PA3-900 detects calreticulin from human, non-human primate, rabbit, mouse, canine and rat samples. PA3-900 has been successfully used in Western blot, immunofluorescence, immunocytochemistry, flow cytometry, and immunoprecipitation procedures. By Western blot, this antibody detects an ~60 kDa protein representing calreticulin from rat brain extract. Immunofluorescence staining of calreticulin in rat brain cortex with PA3-900 results in fine granular staining consistent with ER localization. PA3-900 immunogen is recombit human calreticulin protein produced in the Baculovirus insect cell system.Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.
|whole serum with 0.05% sodium azide|
|P28490, P27797, P14211, P15253, P18418|
|Calregulin, CRP55, CaBP3, Calsequestrin-Like Protein, Ro/SS-A Antigen, Calr|
|Canine, Human, Mouse, Non-human primate, Rabbit, Rat|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|Recombit, human calreticulin protein.|
|-20° C, Avoid Freeze/Thaw Cycles|
|100009050, 12317, 476694, 64202, 811|
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