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Calreticulin Rabbit anti-Canine, Human, Mouse, Non-human primate, Rabbit, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA3900

Catalog No. PA3900


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Description

Description

PA3-900 detects calreticulin from human, non-human primate, rabbit, mouse, canine and rat samples. PA3-900 has been successfully used in Western blot, immunofluorescence, immunocytochemistry, flow cytometry, and immunoprecipitation procedures. By Western blot, this antibody detects an ~60 kDa protein representing calreticulin from rat brain extract. Immunofluorescence staining of calreticulin in rat brain cortex with PA3-900 results in fine granular staining consistent with ER localization. PA3-900 immunogen is recombit human calreticulin protein produced in the Baculovirus insect cell system.

Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.
Specifications

Specifications

Calreticulin
Polyclonal
whole serum with 0.05% sodium azide
P28490, P27797, P14211, P15253, P18418
Calregulin, CRP55, CaBP3, Calsequestrin-Like Protein, Ro/SS-A Antigen, Calr
Rabbit
IgG
RUO
Antibody
Polyclonal
Canine, Human, Mouse, Non-human primate, Rabbit, Rat
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
CALR
Liquid
CALR
Recombit, human calreticulin protein.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
100009050, 12317, 476694, 64202, 811
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