Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CaMKIV Rabbit anti-Canine, Human, Mouse, Non-human primate, Plant, Rat, Xenopus laevis, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA1542

Catalog No. PA1542

Add to cart



PA1-542 detects CaM kinase IV (CaMKIV) from human, mouse, rat, canine, primate, arabidopsis and Xenopus Oocyte samples. PA1-542 has been successfully used in Western blot and immunohistochemistry procedures. By Western blot, this antibody detects an ~55 kDa protein representing CaMKIV in HeLa cell lysate. PA1-542 immunizing peptide corresponds to amino acid residues 127-143 from mouse CaMKIV. This sequence is 94% conserved in rat and human CaMKIV. This peptide (Cat. PEP-109) is available for use in neutralization and control experiments.

CaM kinase IV (CaMKIV), in a calcium and calmodulin dependent manner, is implicated in phosphorylating numerous transcription factors including the CCAAT enhancer binding protein (C/EBP), serum response factor (SRF), and cyclic AMP response element binding protein (CBP). The nuclear localization of this protein is consistent with its role in mediating calcium-dependent gene expression. CaMKIV is particularly abundant in testis, T-cells, and neurons but is also found in other tissues to varying degrees. In neurons, CaMKIV is thought to play an important role in synaptic plasticity via its gene regulatory effects. In T-cells, this protein plays an important role in calcium signaling which could affect the transcription regulatory protein, nuclear factor of activated T-cells (NFAT). CaMKIV is encoded, along with calspermin, by the CaMKIV gene. It has been found that, in testes, CaMKIV is expressed in germ cells and found to be associated with chromatin. The association of CaMKIV with chromatin suggests a potential role in chromatin remodeling during nuclear condensation in spermatids.


CAMK4, camk4.L
Synthetic Peptide: V(127) E K G Y Y S E R D A A D A V K Q(143) C
Antigen affinity chromatography
Canine, Human, Mouse, Non-human primate, Plant, Rat, Xenopus laevis
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide
Q16566, P08414, P13234
CaMKIV, Brain Ca(2+) calmodulin dependent protein kinase type, Calcium / calmodulin dependent protein kinase type 4 catalytic chain, Calcium/calmoduli
100 μg
-20° C, Avoid Freeze/Thaw Cycles
100684140, 12326, 25050, 373837, 814
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit