Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CAMLG Mouse anti-Human, Clone: 3F12, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA518533

Catalog No. PIMA518533


Add to cart

Description

Description

Peptide Sequence: MESMAVATDG GERPGVPAGS GLSASQRRAE LRRRKLLMNS EQRINRIMGF HRPGSGAEEE SQTKSKQQDS DKLNSLSVPS VSKRVVLGDS VSTGTTDQQG

The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
Specifications

Specifications

CAMLG
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
P49069
CAML, calcium signal-modulating cyclophilin ligand, calcium-modulating cyclophilin ligand, calcium-signal modulating cyclophilin ligand, cyclophilin B-binding protein
Mouse
IgG2b, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
819
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
3F12
Unconjugated
CAMLG
Liquid
CAMLG
CAMLG (NP_001736, 1 a.a. ∽ 100 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit