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CAPS1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520516

Catalog No. PIPA520516


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Description

Description

A suggested positive control is rat brain tissue lysate. PA5-20516 can be used with blocking peptide PEP-0636.

CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4, 5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion.
Specifications

Specifications

CAPS1
Polyclonal
Unconjugated
CADPS
Liquid
CADPS
A 20 amino acid peptide near the carboxy terminus of the human CAPS1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9ULU8, Q80TJ1, Q62717
CADPS1, CAPS, CAPS1; CAPS-1; Ca2+-dependent activator protein for secretion; Ca2+-dependent secretion activator; Ca2+-regulated cytoskeletal protein; calcium-dependent activator protein for secretion 1; calcium-dependent secretion activator 1
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
26989, 27062, 8618
Documents
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