CAPS1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520517
A suggested positive control is rat brain tissue lysate. PA5-20517 can be used with blocking peptide PEP-0637.CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4, 5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion.
|A 21 amino acid peptide near the amino terminus of the human CAPS1.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|Q9ULU8, Q80TJ1, Q62717|
|CADPS1, CAPS, CAPS1; CAPS-1; Ca2+-dependent activator protein for secretion; Ca2+-dependent secretion activator; Ca2+-regulated cytoskeletal protein; calcium-dependent activator protein for secretion 1; calcium-dependent secretion activator 1|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|26989, 27062, 8618|
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