CES1 Mouse anti-Human, Clone: 544623, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524244
In direct ELISAs and Western blots, 100% cross-reactivity with recombit mouse (rm) CES-3 and no cross-reactivity with rmCES-2, rmCES-5, or recombit human CES-2 is observed. Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
|PBS with 5% trehalose and No Preservative|
|ACAT, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, acyl coenzyme A:cholesterol acyltransferase, acyl-coenzyme A:cholesterol acyltransferase, brain carboxylesterase hBr1, carboxylesterase 1 (monocyte/macrophage serine esterase 1), carboxylesterase 2 (liver), cholesteryl ester hydrolase, cocaine carboxylesterase,|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunoprecipitation, Western Blot|
|Mouse myeloma cell line NS0-derived recombit human Carboxylesterase1/CES-1 His19-Glu563|
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