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CES1 Mouse anti-Human, Clone: 544623, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524244

Catalog No. PIMA524244


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Description

Description

In direct ELISAs and Western blots, 100% cross-reactivity with recombit mouse (rm) CES-3 and no cross-reactivity with rmCES-2, rmCES-5, or recombit human CES-2 is observed. Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
Specifications

Specifications

CES1
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P23141
ACAT, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, acyl coenzyme A:cholesterol acyltransferase, acyl-coenzyme A:cholesterol acyltransferase, brain carboxylesterase hBr1, carboxylesterase 1 (monocyte/macrophage serine esterase 1), carboxylesterase 2 (liver), cholesteryl ester hydrolase, cocaine carboxylesterase,
Mouse
IgG2B
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
1066
Immunoprecipitation, Western Blot
544623
Unconjugated
CES1
Lyophilized
CES1
Mouse myeloma cell line NS0-derived recombit human Carboxylesterase1/CES-1 His19-Glu563
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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