CES2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528027
PA5-28027 targets Carboxylesterase 2 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28027 immunogen is recombit fragment corresponding to a region within amino acids 51 and 469 of Human Carboxylesterase 2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined; however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
|Recombit fragment corresponding to a region within amino acids 51 and 469 of Human Carboxylesterase 2|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|CE-2, CES2A1, PCE-2, iCE, carboxylesterase 2 (intestine, liver), cocaine esterase, hCE-2, intestinal carboxylesterase; liver carboxylesterase-2, methylumbelliferyl-acetate deacetylase 2|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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