CARD9 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA529189
PA5-29191 targets ATP6V1A in IF and WB applications and shows reactivity with Human and mouse samples. The PA5-29191 immunogen is recombit fragment corresponding to a region within amino acids 60 and 344 of Human ATP6V1A.The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.
|Recombit fragment corresponding to a region within amino acids 36 and 249 of Human CARD9|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|CANDF2, hCARD9, caspase recruitment domain-containing protein 9|
|-20° C, Avoid Freeze/Thaw Cycles|
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