CSNK1A1L Rabbit anti-Human, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528272
PA5-28272 targets Casein Kinase 1 alpha 1L in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28272 immunogen is recombit fragment corresponding to a region within amino acids 10 and 228 of Human Casein Kinase 1 alpha 1L. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase I alpha, gamma, delta and epsilon, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair, membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation. Casein kinase I isoform alpha-like (CSNK1A1L) is a 337 amino acid protein that shares a high degree of sequence similarity with the alpha isoform of casein kinase 1. CSNK1A1L resides in the cytoplasm and participates in the Wnt signaling pathway. By utilizing ATP within its protein kinase domain, CSNK1A1L phosphorylates a large number of proteins.
|Recombit fragment corresponding to a region within amino acids 10 and 228 of Human Casein Kinase 1 alpha 1L|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7|
|CK1, CKI-alpha-like, casein kinase I alpha S-like, casein kinase I isoform alpha-like|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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