Caspase 3 (Cleaved Asp175) Rabbit anti-Human, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523921
DescriptionThis gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predomit caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer ft.s disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
|Caspase 3 (Cleaved Asp175)|
|KLH conjugated synthetic peptide between 149-179 amino acids from human CASP3(Asp175)|
|Antigen Affinity Chromatography, Protein A|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.09% sodium azide|
|CPP32, CPP32B, SCA-1, CASP-3, CPP-32, PARP cleavage protease, SREBP cleavage activity 1, Yama, apopain, caspase 3, apoptosis-related cysteine protease, caspase-3, cysteine protease CPP32, procaspase3, protein Yama|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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