anti-Caspase 10 Polyclonal, Thermo Scientific™

Caspase 10 Polyclonal antibody PA1-12507 from Thermo Scientific™ specifically detects Caspase 10 in Human, Mouse and Rat samples, and it is validated for Western Blot

Manufacturer: Invitrogen PA112507

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Catalog No. 01-674-167

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    Specifications

    Antigen Caspase 10
    Applications Western Blotting
    Conjugate Unlabeled
    Cross Reactivity Human,Mouse,Rat
    Format Purified
    Formulation 100μg purified antibody in PBS and 0.02% sodium azide
    Gene Accession No. Q92851
    Gene Alias ALPS2, FLICE2, MCH4
    Gene Symbols CASP10
    Host Species Rabbit
    Immunogen Synthetic peptide corresponding to residues 505-521 of human FLICE2.
    Isotype IgG
    Quantity 100μg
    Species Reactivity Human, Mouse, Rat
    Storage Requirements Avoid Freeze/Thaw Cycles
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Gene ID (Entrez) 843

    Caspase 10 Polyclonal antibody PA1-12507 from Thermo Scientific™ specifically detects Caspase 10 in Human, Mouse and Rat samples, and it is validated for Western Blot

    Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
    Host Species: Rabbit
    Cross Reactivity: Human, Mouse, Rat
    Isotype: IgG
    Immunogen: Synthetic peptide corresponding to residues 505-521 of human FLICE2.
    Formulation: 100µg purified antibody in PBS and 0.02% sodium azide
    Synonyms: ALPS2, FLICE2, MCH4
    Uniprot Accession: Q92851
    Entrez GeneID: 843
    Gene Symbol: CASP10
    A suggested positive control for this product is HeLa whole cell lysate.

  • Description & Specifications

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