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Caspase 10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112507

Catalog No. 01-674-167


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Description

Description

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

A suggested positive control for this product is HeLa whole cell lysate.
Specifications

Specifications

Caspase 10
Polyclonal
PBS with 0.02% sodium azide
Q92851
ALPS2, FLICE2, MCH4
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
843
Western Blot
Unconjugated
CASP10
Liquid
CASP10
Synthetic peptide corresponding to residues 505-521 of human FLICE2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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