Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Caspase 2 Precursor Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112795

Catalog No. 01-675-791


Add to cart

Description

Description

By Western blot, this antibody detects bands at ~40 and ~50 kDa, representing the short and long forms of Caspase 2, respectively.

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
Specifications

Specifications

Caspase 2 Precursor
Polyclonal
Unconjugated
CASP2
Liquid
CASP2
Synthetic peptide corresponding to 16 residues from the N-terminus of human Caspase-2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P42575, P29594
CASP-2, ICH-1L, ICH-1L/1S, ICH1, NEDD2
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
12366, 835
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit