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Caspase 4 Precursor Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112796

Catalog No. 01-675-792


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Description

Description

A suggested positive control for this product is spleen or lung lysate.

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
Specifications

Specifications

Caspase 4 Precursor
Polyclonal
PBS with 0.02% sodium azide
P49662
ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
837
Immunohistochemistry, Western Blot
Unconjugated
CASP4
Liquid
CASP4
Synthetic peptide corresponding to 15 residues from near the center of human Caspase-4.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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