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Caspase 6 Mouse anti-Human, Clone: MCH2 14 1-190, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA112558

Catalog No. 01-674-344


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Description

Description

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

A suggested positive control for this product is MCF-7 cell lysate.
Specifications

Specifications

Caspase 6
Monoclonal
Unconjugated
CASP6
Liquid
CASP6
Recombit human capase-6 protein.
Protein A/G
RUO
Antibody
Monoclonal
Human
Western Blot
MCH2 14 1-190
PBS with 0.08% sodium azide
P55212
MCH2
Mouse
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
839
Documents
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