Caspase 6 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527683
PA5-27683 targets Caspase 6 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27683 immunogen is recombit fragment corresponding to a region within amino acids 1 and 182 of Human Caspase 6. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
|Recombit fragment corresponding to a region within amino acids 1 and 182 of Human Caspase 6|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 20% glycerol and 0.01% thimerosal; pH 7|
|MCH2, apoptotic protease MCH-2, caspase 6, apoptosis-related cysteine protease, caspase-6|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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