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Catenin alpha-1 Rabbit anti-Human, Mouse, Xenopus laevis, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA125081

Catalog No. PIPA125081

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PA1-25081 detects alpha 1 Catenin from human samples. PA1-25081 is expected to cross react with mouse (100% conserved) and Xenopus laevis (100% conserved) due to sequence homology. PA1-25081 has been successfully used in Western blot procedures. The PA1-25081 immunogen is a synthetic peptide, conjugated to KLH, corresponding to residues E(873) K Q D E T Q T K I K R A S Q(887) of human alpha 1 Catenin. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Alpha catenin is a member of the b-catenin family of cytosolic proteins. Alpha catenin interacts with N-cadherin and b-catenin on the cytosolic side of adherins junctions to mediate the interaction with the actin cytoskeleton. Alpha catenin is a homodimer in solution, but dissociates to form a 1:1 heterodimer with b-catenin in order to interact with cadherins. It also regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Alpha catenin also functions in the control of the startle modulation.


Catenin alpha-1
0.01M PBS with 15mM sodium azide; pH 7.4
P35221, P26231
CAP102, FLJ36832, FLJ52416
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
12385, 1495, 399303
Immunocytochemistry, Immunofluorescence, Western Blot
CTNNA1, ctnna1.S
Synthetic peptide, conjugated to KLH, corresponding to residues E(873) K Q D E T Q T K I K R A S Q(887) of human alpha 1 Catenin.
IgG fraction
Human, Mouse, Xenopus laevis
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