beta Catenin Mouse anti-Human, Mouse, Non-human primate, Rat, Clone: 6F9, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA1300
Beta Catenin is thought to play a role in cell-cell communication and adhesion, and possibly cell morphology. In the nucleus, beta Catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation. This influence on cell proliferation is the molecular basis for the role of beta Catenin in tumorgenesis, in particular solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.MA1-300 detects beta Catenin from A431, WI-38, and MCF-7 human cell lines, mouse and rat samples.MA1-300 has been successfully used in Western blot applications. By Western blot this antibody detects a ~94kDa protein representing beta Catenin.The MA1-300 immunogen is recombinant beta Catenin protein.
|PBS with 1mg/mL BSA and 0.05% sodium azide|
|P35222, Q02248, Q9WU82|
|Cadherin associated protein, Catenin beta 1, CATNB, CTNNB|
|Human, Mouse, Non-human primate, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Recombit beta Catenin protein.|
|-20° C, Avoid Freeze/Thaw Cycles|
|12387, 1499, 84353|
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