delta Catenin Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA139454
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is breast lobular carcinoma.Catenin delta (p120) is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.
|PBS with 1% BSA and 0.1% sodium azide|
|CAS, CTNND, P120CAS, P120CTN, p120, p120CAS, p120CTN, cadherin-associated Src substrate, catenin delta-1, p120 catenin|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Synthetic peptide corresponding to C-terminus of human p120.|
|Antigen affinity chromatography|
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