Cathepsin L Mouse anti-Insect, Clone: 193702, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523929
In Western blots, less than 5% cross-reactivity with recombit human Cathepsin L is observed and no cross-reactivity with recombit mouse Cathepsin L is observed. Reconstitute at 0.5 mg/mL in sterile PBS.The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.
|PBS with 5% trehalose and No Preservative|
|Cathepsin L heavy chain; Cathepsin L light chain; CATL; CTSL|
|Sf 21-derived Insect Cathepsin L|
|Immunoprecipitation, Western Blot|
|-20° C, Avoid Freeze/Thaw Cycles|
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