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Cav1.2 Polyclonal Antibody, Invitrogen™

Cav1.2 Antibody, PA5-23013, from Invitrogen™. Species Reactivity: Human, Mouse, Rabbit, Rat; Applications: Blocking Assay, Immunoprecipitation, Neutralization, Western Blot.

Manufacturer:  Invitrogen PA523013

Catalog No. PIPA523013

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Cav1.2 Antibody, PA5-23013, from Invitrogen. Species Reactivity: Human, Mouse, Rabbit, Rat; Applications: Blocking Assay, Immunoprecipitation, Neutralization, Western Blot.

CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by CACNA1C this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins.
Host Species: Rabbit
Cross Reactivity: Human, Mouse, Rabbit, Rat
Isotype: IgG
Immunogen: Synthetic peptide made to an internal portion of rat CACNA1C (within residues 1150-1200).
Formulation: 100µL purified antibody (1mg/mL) in PBS and 0.1% sodium azide
Synonyms: CACH2, CACN2, CACNL1A1, CCHL1A1, CaV1.2, TS, DHPR, alpha-1 subunit, calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit, voltage-dependent L-type calcium channel subunit alpha-1C, voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*
Uniprot Accession: P15381, P22002, Q01815, Q13936
Entrez GeneID: 100101555, 100144322, 12288, 24239, 775
Gene Symbol: CACH2C, CACNA1C
This product detects Cav1.2 in Human, Mouse, Rabbit and Rat samples. This product has been successfully used in Blocking Assay, Immunoprecipitation, Neutralization and Western Blot procedures. The immunogen is Synthetic peptide made to an internal portion of rat CACNA1C (within residues 1150-1200)..
Specifications

Specifications

Cav1.2
Polyclonal
100μL purified antibody (1mg/mL) in PBS and 0.1% sodium azide
Purified
CACH2C, CACNA1C
Synthetic peptide made to an internal portion of rat CACNA1C (within residues 1150-1200).
100μL
Store at -20°C
Primary
100101555, 100144322, 12288, 24239, 775
Blocking Assay, Immunoprecipitation, Neutralization, Western Blot
Unconjugated
P15381, P22002, Q01815, Q13936
CACH2, CACN2, CACNL1A1, CCHL1A1, CaV1.2, TS, DHPR, alpha-1 subunit, calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit, voltage-dependent L-type calcium channel subunit alpha-1C, voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*
Rabbit
IgG
RUO
Primary
Polyclonal
Human, Murine, Rabbit, Rat
Documents
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