Caveolin 1 Goat anti-Human, Polyclonal, Invitrogen
Goat Polyclonal Antibody
Manufacturer: Invitrogen PA19021
This antibody is predicted to react with canine, mouse, porcine and rat based on sequence homology.Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.
|Internal sequence corresponding to amino acids C-DELSEKQVYDAH.|
|Antigen affinity chromatography|
|TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3|
|CAV1; caveolin 1, caveolae protein, 22kDa ; HGNC:1527; CAV; MSTP085; VIP21 ; caveolae protein, 22-kD; caveolin 1; caveolin 1 caveolae protein, 22kD; c|
|-20° C, Avoid Freeze/Thaw Cycles|
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