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CBL, Mouse, Clone: 6D12, Abnova™

Mouse monoclonal antibody raised against a partial recombinant CBL.

Manufacturer:  Abnova Corporation H00000867M01A

Catalog No. 89-016-463


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Specifications

Description

The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq

Sequence: NIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSER
Description & Specifications

Specifications

CBL
6D12
Human
Liquid
CBL
C-CBL, CBL2, RNF55
Murine
IgG1, κ
RUO
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
ELISA,Immunoprecipitation,Western Blot
Unlabeled
Cas-Br-M (murine) ecotropic retroviral transforming sequence
In ascites fluid
NM_005188
CBL
CBL (NP_005179, 736 a.a. ∽836 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26kDa.
200μL
Human
Primary
867
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