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HP1 beta Mouse anti-Human, Clone: 4E12, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA521203

Catalog No. PIMA521203


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Description

Description

Peptide Sequence: GKKQNKKKVE EVLEEEEEEY VVEKVLDRRV VKGKVEYLLK WKGFSDEDNT WEPEENLDCP DLIAEFLQSQ KTAHETDKSE GGKRKADSDS EDKGEESK

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Specifications

Specifications

HP1 beta
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.4
P83916
CBX1; HP1-BETA; chromobox homolog 1 (HP1 beta homolog Drosophila ); HGNC:1551; CBX; HP1Hs-beta; M31; MOD1; chromobox homolog 1 (Drosophila HP1 beta); heterochromatin protein p25 beta; HP1Hsbeta; p25beta; heterochromatin protein 1-beta; modifier 1 protein
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
10951
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
4E12
Unconjugated
CBX1
Liquid
CBX1
CBX1 (NP_006798.1, 2 a.a. ∽ 99 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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