HP1 beta Mouse anti-Human, Clone: 4E12, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA521203
Peptide Sequence: GKKQNKKKVE EVLEEEEEEY VVEKVLDRRV VKGKVEYLLK WKGFSDEDNT WEPEENLDCP DLIAEFLQSQ KTAHETDKSE GGKRKADSDS EDKGEESKThis gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.
|PBS with no preservative; pH 7.4|
|CBX1; HP1-BETA; chromobox homolog 1 (HP1 beta homolog Drosophila ); HGNC:1551; CBX; HP1Hs-beta; M31; MOD1; chromobox homolog 1 (Drosophila HP1 beta); heterochromatin protein p25 beta; HP1Hsbeta; p25beta; heterochromatin protein 1-beta; modifier 1 protein|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Immunocytochemistry, Immunofluorescence, Western Blot|
|CBX1 (NP_006798.1, 2 a.a. ∽ 99 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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