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HP1 alpha Rabbit anti-Canine, Human, Mouse, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523358

Catalog No. PIPA523358


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Description

Description

CBX5, also known as Chromobox protein homolog 5, is a regulatory protein belonging to the Polycomb group proteins family with two chromo domains. CBX5 associates with chromosomes during mitosis, specifically with chromatin during metaphase and anaphase. A component of the centromeric and pericentromeric heterochromatin, CBX5 may interact with lamin B receptor (LBR) to contribute to the association of the heterochromatin with the inner nuclear membrane. CBX5 recognizes and binds histone H3 tails methylated at  ft.Lys-9 ft., leading to epigenetic repression. This methyl-lysine binding protein localized at heterochromatin sites is also known to mediate gene silencing and is involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Specifications

Specifications

HP1 alpha
Polyclonal
Unconjugated
CBX5
Liquid
CBX5
Synthetic peptide (76 GENNKPREKSESNKRK 91) of CBX5 protein.
Protein A
RUO
Antibody
Polyclonal
Canine, Human, Mouse, Non-human primate
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
P45973, Q61686
HP1, HP1A, HP1 alpha homolog, HP1-ALPHA, HP1Hs alpha, antigen p25, chromobox homolog 5 (HP1 alpha homolog, Drosophila), chromobox protein homolog 5, heterochromatin protein 1 homolog alpha, heterochromatin protein 1-alpha
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
12419, 23468, 477593
Documents
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