HP1 alpha Rabbit anti-Canine, Human, Mouse, Non-human primate, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523358
DescriptionCBX5, also known as Chromobox protein homolog 5, is a regulatory protein belonging to the Polycomb group proteins family with two chromo domains. CBX5 associates with chromosomes during mitosis, specifically with chromatin during metaphase and anaphase. A component of the centromeric and pericentromeric heterochromatin, CBX5 may interact with lamin B receptor (LBR) to contribute to the association of the heterochromatin with the inner nuclear membrane. CBX5 recognizes and binds histone H3 tails methylated at ft.Lys-9 ft., leading to epigenetic repression. This methyl-lysine binding protein localized at heterochromatin sites is also known to mediate gene silencing and is involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
|Synthetic peptide (76 GENNKPREKSESNKRK 91) of CBX5 protein.|
|Canine, Human, Mouse, Non-human primate|
|PBS with 0.05% BSA and 0.05% sodium azide|
|HP1, HP1A, HP1 alpha homolog, HP1-ALPHA, HP1Hs alpha, antigen p25, chromobox homolog 5 (HP1 alpha homolog, Drosophila), chromobox protein homolog 5, heterochromatin protein 1 homolog alpha, heterochromatin protein 1-alpha|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|12419, 23468, 477593|
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