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Uteroglobin Mouse anti-Human, Clone: AY1E6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA140223

Catalog No. 01-676-563


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Description

Description

MA1-40223 detects CC16 from human samples. MA1-40223 has been successfully used in ELISA, immunohistochemistry (frozen and paraffin) and Western blot applications. The MA1-40223 immunogen is human CC16.

Clara cell protein (CC16) or urinary protein 1 is a homodimeric protein of 16 kD and is secreted predomitly by Clara cells in terminal bronchioles and from puberty on in the male urogenital tract. CC16 is formed by two chains, each with a molecular weight of 7.9 kD. CC16 occurs in very high concentrations in respiratory tract derived fluids such as sputum or bronchoalveolar lavage fluid. CC16 occurs also in urogenital secretions, such as amniotic fluid, urine and semen. The protein difusses passively into serum. CC16 behaves like an anti-cytokine by downregulating the production of IFNgamma, IL-1 and TNF-alpha by stimulated leukocytes. Besides this, CC16 reduces the antiviral activity and the augmentation of phagocytosis induced by IFN-gamma.
Specifications

Specifications

Uteroglobin
Monoclonal
0.1 mg/mL
PBS with 0.1% BSA and 0.02% sodium azide
P11684
SCGB1A1
Mouse
IgG1
100 μg
4° C
Primary
7356
ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
AY1E6
Unconjugated
SCGB1A1
Liquid
SCGB1A1
Human CC16.
Protein G
RUO
Antibody
Monoclonal
Human
Documents
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