Uteroglobin Mouse anti-Human, Clone: AY1E6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA140223
MA1-40223 detects CC16 from human samples. MA1-40223 has been successfully used in ELISA, immunohistochemistry (frozen and paraffin) and Western blot applications. The MA1-40223 immunogen is human CC16.Clara cell protein (CC16) or urinary protein 1 is a homodimeric protein of 16 kD and is secreted predomitly by Clara cells in terminal bronchioles and from puberty on in the male urogenital tract. CC16 is formed by two chains, each with a molecular weight of 7.9 kD. CC16 occurs in very high concentrations in respiratory tract derived fluids such as sputum or bronchoalveolar lavage fluid. CC16 occurs also in urogenital secretions, such as amniotic fluid, urine and semen. The protein difusses passively into serum. CC16 behaves like an anti-cytokine by downregulating the production of IFNgamma, IL-1 and TNF-alpha by stimulated leukocytes. Besides this, CC16 reduces the antiviral activity and the augmentation of phagocytosis induced by IFN-gamma.
|PBS with 0.1% BSA and 0.02% sodium azide|
|ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot|
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