CCDC106 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521003
A suggested positive control is human brain tissue lysate. PA5-21003 can be used with blocking peptide PEP-1117.The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.
|A 15 amino acid peptide near the carboxy terminus of human CCDC106.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|HSU79303, ZNF581; coiled-coil domain-containing protein 106; protein predicted by clone 23882|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|232821, 29903, 499071|
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